Promotion in Bio- und Chemiewissenschaften

https://www.sydney.edu.au/scholarships/d/postgraduate-research-scholarship-in-stem-cell-biology.html

This Scholarship aims to support a student undertaking a Masters by Research or Doctor of Philosophy (PhD) within the School of Life and Environmental Sciences, Faculty of Science, where the focus of their research is on characterising the functional behaviour of human stem cells in response to the extracellular matrix protein, tropoelastin.

This Scholarship is co-funded by the Australian Research Council through Discovery Project (DP220101644) and NHMRC Investigator Grant Emerging Leadership (EL1) for the project: Functional amplification of stem cells for tissue repair.

The project seeks to investigate how adult stem cells receive and interpret mechanical or biochemical signals from matrix proteins such as tropoelastin, to stimulate or enhance a broad range of biological functions, including self-renewal, multi-lineage plasticity, and the secretion of cell-instructive factors. This work will contribute towards the understanding of natural mechanisms that modulate stem cell biology, with applications towards the production of stem cells possessing superior regenerative potential for tissue repair.

Benefits

The Scholarship will provide a stipend allowance equivalent to $29,507 per annum (fixed rate), subject to satisfactory academic performance:

I. up to 1.75 years for a successful Master’s by research recipient.

II. up to 3 years for a successful PhD recipient.

International recipients may be eligible for Faculty of Science Research Tuition Fee Scholarship, subject to approval.

We are currently looking for a PhD candidate to join our research team in the examination of feral cat distribution in Australia using ancient DNA (aDNA) techniques. The primary focus of this role is to investigate the impact of feral cats on the Australian ecosystem during the Anthropocene, the current geological age characterised by significant human impact on the planet. This project includes analysing aDNA from cat remains obtained from various archaeological and palaeontological sites across Australia to reconstruct the historical distribution and genetic diversity of feral cats. Success in this role requires collaboration with interdisciplinary experts in archaeology, genetics, and palaeoecology, as well as with Indigenous communities to ensure the ethical and respectful use of cultural heritage materials.This project will be undertaken through the Australian Research Centre for Human Evolution (ARCHE), with cross supervision from the Griffith Centre for Social and Cultural Research (GCSCR) and the Department of Archaeology, Max Planck Institute of Geoanthropology, Germany.

ARCHE is a world leader in research and education on all aspects of human evolutionary studies. We provide a dynamic and cooperative research environment that seeks to understand how humans and their societies across the globe evolved over time. We emphasise the study of the biological and cultural evolution of humans and our place in the natural world, with a growing focus on Indigenous peoples of Australia, Asia, and the Pacific. A/Prof Julien Louys and Dr Mark de Bruyn are based in ARCHE and together have a wealth of experience in studying past environmental change, human-faunal interactions through time, and the use of genetic and phylogenetic data to examine evolutionary questions. Dr Tim Maloney is based in GCSCR and an affiliate member of ARCHE and has been working on the archaeology of Australia for nearly 10 years and has a keen interest in the management of feral cat species. Professor Nicole Boivin’s research explores how archaeological data can inform present-day issues ranging from climate change and the Anthropocene to globalization, food security and migration.

The living allowance stipend will be $32,192 per annum tax-free for three years (2023 rate, indexed annually). Project funding to undertake the research, conference travel and incidentals is also provided.

A successful international applicant will also be awarded a Griffith University International Postgraduate Research Scholarship to cover tuition fees for up to three years (noting the onshore requirement mentioned previously). Please see the GUIPRS Conditions of Award for more information.

The selection of applicants for the award of higher degree research scholarships at Griffith University involves consideration of your academic merit and research background. To be successful research project on aDNA and the impact of feral cats in Australia, you will be able to demonstrate a strong foundation in genetics and molecular biology, as well as familiarity with conservation biology, archaeology/palaeontology, and wildlife management. You will have evidence of a passion for biodiversity conservation and a desire to address the negative impact of feral cats on Australian wildlife. You will ideally have experience in fieldwork, data collection, and analysis, as well as the ability to work independently and collaboratively with stakeholders from diverse backgrounds. with a strong desire to undertake research in making a positive impact on the environment.

Qualifications
Expressions of interest are welcome from domestic and international applicants.
Applicants must have completed, or expect to complete, a bachelors degree with honours equivalent to first class honours or a Masters degree (AQF Level 9) incorporating a significant research component of a standard comparable to a bachelor honours degree or be regarded by Griffith University as having an equivalent level of attainment in accordance with Schedule One of the HDR Scholarship Policy. For further information on the eligibility requirements for the program refer here.
International applicants should ensure that English Language Proficiency requirements for the program are met before formally applying. Applicants to research programs will need to show they meet:

• A minimum overall band score of 6.5 on the IELTS (Academic) with no band score less than 6.0 OR
• A minimum score of 575 on the paper-based TOEFL including a score of no less than 5.0 on the TWE OR
• A score of 79 on the internet-based (iBT) TOEFL with no sub-score less than 19

Are you an engineer, software developer, or perhaps the AI wizard looking to make a big impact in environmental sciences and drug discovery? We have an exciting PhD project that is perfect for you!

We are seeking talented and innovative PhD candidates to develop algorithms that enable video-based real-time tracking of aquatic model organisms in complex environments on a large scale. This interdisciplinary project will pioneer new algorithms and innovative methods to provide the world's first inherently scalable behavioral bioanalysis, unlocking cognitive research in aquatic eco-neurotoxicology and neuroactive drug discovery. Additionally, the outcomes of the project will enable novel scientific discoveries in neurobiology research on aquatic animals.

The lack of automated and high-throughput cognitive tests in aquatic model organisms is a major deficiency, but with your help, we can change that. This project will provide the first-ever unbiased and automated analytical systems for cognitive eco- & neurotoxicology, allowing us to assess how diverse neuroactive pollutants and/or drugs affect higher neurological functions of aquatic animals.

Don't miss this opportunity to be at the forefront of ground-breaking research at the Neurotox Lab at RMIT University. As one of Australia's leading experts in eco-neurotoxicology, we are exploring how pollutants impact animal behavior and neurodevelopment, as well as elucidating the neurobiological foundations underlying changes in animal behavior.

By joining this PhD project, you will have the opportunity to work in an exciting and rapidly growing interdisciplinary field. Apply now and join us in making a difference in the world.

The applicants can apply for RMIT Higher Degree by Research International Scholarship upon being granted an offer of admission to an RMIT research training program. The deadline for the next International Scholarship round will be 15th September 2023.

Preparative chromatography is a key unit operation in biopharmaceutical manufacturing. Flow rate gradients can further improve process economics. This project aims to extend current mechanistic models to precisely model flow rate variations as well as investigate the influence of flow rate gradients on preparative chromatography.

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

The mechanical stimuli generated by body exercise can be transmitted from cortical bone into the deep bone marrow. A mechanosensitive perivascular stem cell niche is recently identified within the bone marrow for osteogenesis and lymphopoiesis. However, the mechanopropagation from compact bone to deep bone marrow vasculature remains elusive in this fundamental mechanobiology field. No experimental system is available yet to directly understand such exercise‐induced mechanopropagation at the bone‐vessel interface. To this end, an integrated computational biomechanics framework to quantitatively evaluate the mechanopropagation capabilities of bone marrow arterioles, arteries, and sinusoids is devised. The 3D geometries of blood vessels are smoothly reconstructed in the presence of vessel wall thickness and intravascular pulse pressure, followed by finite element analysis to thoroughly investigate the mechanical effects of exercise‐induced intravascular vibratory stretching on bone marrow vasculature. The effects of blood pressure and cortical bone bending are also examined. It is concluded that arterioles and arteries are much more efficient in transducing mechanical force than sinusoids due to their higher stiffness. In the future, this in-silico approach could be combined with other clinical imaging modalities for subject/patient‐specific vascular reconstruction and biomechanical analysis, providing large‐scale phenotypic data for personalized mechanobiology discovery.

The Scholarship will provide a stipend allowance equivalent to the University of Sydney’s Research Training Program (RTP) stipend rate for up to 3.5 years.

RTP stipend is currently $35,950 AUD/year.

The scholarship is available to domestic and international students.

Clotting and bleeding are two sides of a coin, leading to cardiovascular diseases such as stroke and haemophilia—the No.1 worldwide killer. It has long been recognised that the von Willebrand factor (VWF) is the mechanosensor for primary and secondary haemostasis by interacting with platelets and clotting factor VIII. We have recently discovered a new ‘biomechanical’ prothrombotic mechanism that highlights the remarkable VWF sensitivity to the shear stress of blood flow disturbance. Importantly, we found that the current drugs are often not successful and come with an increased financial burden.
To address this pressing need, we are establishing a GPU accelerated multi-scale simulation platform to unveil the effects of blood flow disturbance at the single-molecule level. For the first time, fluid mechanics and biochemistry fields will be united in silico to correlate the haemodynamic parameters with clotting and bleeding disorders.

The Scholarship will provide a stipend allowance equivalent to the University of Sydney’s Research Training Program (RTP) stipend rate for up to 3.5 years.

RTP stipend is currently $35,950 AUD/year.

The scholarship is available to domestic and international students.

You will have:
• Academic knowledge in the discipline of biophysics, biomechanics, electrophysiology, cell biology and biochemistry;
• Experience of Linux/Unix commanding line (Unix shell)
• Capability of using two or more of GROMACS, Hex, LabVIEW, Python, AutoCAD, MATLAB and other software.

Preferred experience include:
• Solid basic knowledge of biology and hands-on experience in PC2 biological laboratory, using flow cytometer, ELISA, Western blots, protein-protein interaction assays, protein/antibody purification and functional characterizations;
• Experience in theoretical simulation using and MATLAB or COMSOL, or LabVIEW programming to control equipment and devices.
• Capability of independently output processing models and drawings, be capable of CNC programming, use other conventional processing platform equipment to manufacture mechanical parts, and use 3D printers for part manufacturing.
• Pre-doctoral track records with publications, conference papers, reports, professional or technical contributions with evidence of independent research ability.
• Excellent oral and written communication skills.

GOstralia! Research Centre Scholarships

More info on the novel dating methods can be found in:

www.sciencedirect.com/science/article/pii/S0009254121002436

onlinelibrary.wiley.com/doi/full/10.1111/ter.12580

gchron.copernicus.org/articles/4/353/2022/

www.lyellcollection.org/doi/10.1144/SP537-2022-205

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

GOstralia! Research Centre Scholarships

Looking to make a real difference in the world of environmental science? Join the Neurotox Lab at RMIT University and help us tackle the urgent issue of aquatic pollution. With an ever-increasing number of contaminants entering our waterways, we need your help to understand the ecological and behavioral consequences of exposure to these substances.

As a PhD candidate in our lab, you'll have the opportunity to focus on aquatic animals that interest you, from planarians and crustaceans to insects, snails, and fish. With access to cutting-edge techniques in behavioral ecotoxicology, you'll be able to investigate how exposure to emerging toxicants like pharmaceuticals, PFAS, and micro-/nanoplastics can impact animal behavior at the most fundamental, functional level.

Using state-of-the-art video tracking and advanced biotests, you'll develop new insights into the functional effects of contaminants on animal behavior. From unstimulated behaviors to phototaxis, thermal preference and cognitive responses, you'll explore a wide range of behavioral phenotypes, and help us identify the unique neurobiological mechanisms that underlie these changes.

At the Neurotox Lab, you'll be part of a world-class team who are making a real difference in the emerging field of eco-neurotoxicology. With a focus on understanding the complex relationships between pollution, animal behavior, and ecological consequences, we're helping to shape the future of environmental science.

So if you're looking for a PhD project that can truly make a difference, join us today on a great science adventure in Australia and become part of the solution to environmental challenges.

The applicants can apply for RMIT Higher Degree by Research International Scholarship upon being granted an offer of admission to an RMIT research training program. The deadline for the next International Scholarship round will be 15th September 2023.

Attention all PhD candidates with a passion for aquatic animals and the environment! We have an exciting opportunity for you to pioneer a ground-breaking project that will unlock the secrets of thermal preference behaviors in aquatic animals.

This multi-species screening project will uncover the intertwined aspects of temperature sensing and neuronal data processing that are fundamental for dynamic thermal adaptations and ecological fitness.

You will be part of an interdisciplinary team at the Neurotox Lab at RMIT University, one of Australia's leading experts in eco-neurotoxicology. Using state-of-the-art techniques including quantitative computer animal tracking, you will undertake a pioneering multi-species screening of thermotactic responses in aquatic animals, from native Australian invertebrates to fish. This part of the project will lay the foundation for the development of innovative ecotoxicity biotests.

But the project doesn't stop there! In the following stages, you will explore and make new discoveries on how exposure to emerging contaminants, such as pharmaceuticals, PFAS, and micro/nanoplastics, can alter thermal preference behaviors. This is of considerable importance, as thermal preference behaviors in aquatic animals can become key behavioral factors in toxicological assessment.

Join us at the forefront of this exciting and rapidly growing interdisciplinary field, and be part of a team that is making a difference in the world. Apply now to the Neurotox Lab at RMIT University and discover the world of thermal preference behaviors in aquatic animals.

The applicants can apply for RMIT Higher Degree by Research International Scholarship upon being granted an offer of admission to an RMIT research training program. The deadline for the next International Scholarship round will be 15th September 2023.