Promotion in Bio- und Chemiewissenschaften

Promotion in Bio- und Chemiewissenschaften

Forschungsschwerpunkte

Innerhalb der Bio- und Chemiewissenschaften gibt es verschiedene Möglichkeiten der Spezialisierung. Folgende Forschungsbereiche lassen sich unter anderem diesem Studienfeld zuordnen.

Biowissenschaften:

  • Biochemistry
  • Bioinformatics
  • Biotechnology
  • Cell Biology
  • Ecology
  • Evolutionary Biology
  • Experimental Biology
  • Genetics
  • Immunology
  • Marine Science
  • Microbiology & Molecular Biology
  • Neuro Science
  • Plant Biology
  • Stem Cell Research
  • Structural Biology
  • Zoology

Chemiewissenschaften:

  • Advanced Materials Chemistry & Nanoscience
  • Analytical & Bioanalytical Chemistry
  • Chemical Theory & Computation
  • Biological & Medicinal Chemistry
  • Energy & Catalysis
  • Environmental Chemistry
  • Inorganic & Organic Chemistry
  • Molecular Design & Synthesis
  • Physical & Theoretical Chemistry
  • Polymer Chemistry

Dein genaues Forschungsthema kannst du in direkter Absprache mit den potentiellen Supervisor:innen abstimmen. Falls du noch keine feste Vorstellung für dein Thema hast, schau dir gerne einige der aktuell ausgeschriebenen Projekte an.

Auswahl möglicher Forschungsprojekte in Australien

PhD Bio, Chemie

University:University of Sydney
Faculty:Faculty of Science
Project Start Date:01.07.2023
Application Deadline:19.06.2023
Supervisor Name:Giselle Yeo [email protected]
Location (City/Campus):Camperdown, Sydney
Description:

https://www.sydney.edu.au/scholarships/d/postgraduate-research-scholarship-in-stem-cell-biology.html

This Scholarship aims to support a student undertaking a Masters by Research or Doctor of Philosophy (PhD) within the School of Life and Environmental Sciences, Faculty of Science, where the focus of their research is on characterising the functional behaviour of human stem cells in response to the extracellular matrix protein, tropoelastin.

This Scholarship is co-funded by the Australian Research Council through Discovery Project (DP220101644) and NHMRC Investigator Grant Emerging Leadership (EL1) for the project: Functional amplification of stem cells for tissue repair.

The project seeks to investigate how adult stem cells receive and interpret mechanical or biochemical signals from matrix proteins such as tropoelastin, to stimulate or enhance a broad range of biological functions, including self-renewal, multi-lineage plasticity, and the secretion of cell-instructive factors. This work will contribute towards the understanding of natural mechanisms that modulate stem cell biology, with applications towards the production of stem cells possessing superior regenerative potential for tissue repair.

Funding Information:

Benefits


The Scholarship will provide a stipend allowance equivalent to $29,507 per annum (fixed rate), subject to satisfactory academic performance:

I. up to 1.75 years for a successful Master’s by research recipient.

II. up to 3 years for a successful PhD recipient.

International recipients may be eligible for Faculty of Science Research Tuition Fee Scholarship, subject to approval.

Additional Information:https://www.sydney.edu.au/scholarships/d/postgraduate-research-scholarship-in-stem-cell-biology.html
Categories : PhD Health Sciences | PhD Bio, Chemie | SYD Projects
Griffith University Logo
University:Griffith University
Faculty:Australian Research Centre for Human Evolution (ARCHE)
Project Start Date:03.07.2023
Application Deadline:30.06.2023
Supervisor Name:A/Professor Julien Louys, Email: [email protected]
Location (City/Campus):Brisbane/Nathan Campus
Project Description:

We are currently looking for a PhD candidate to join our research team in the examination of feral cat distribution in Australia using ancient DNA (aDNA) techniques. The primary focus of this role is to investigate the impact of feral cats on the Australian ecosystem during the Anthropocene, the current geological age characterised by significant human impact on the planet. This project includes analysing aDNA from cat remains obtained from various archaeological and palaeontological sites across Australia to reconstruct the historical distribution and genetic diversity of feral cats. Success in this role requires collaboration with interdisciplinary experts in archaeology, genetics, and palaeoecology, as well as with Indigenous communities to ensure the ethical and respectful use of cultural heritage materials.This project will be undertaken through the Australian Research Centre for Human Evolution (ARCHE), with cross supervision from the Griffith Centre for Social and Cultural Research (GCSCR) and the Department of Archaeology, Max Planck Institute of Geoanthropology, Germany.

ARCHE is a world leader in research and education on all aspects of human evolutionary studies. We provide a dynamic and cooperative research environment that seeks to understand how humans and their societies across the globe evolved over time. We emphasise the study of the biological and cultural evolution of humans and our place in the natural world, with a growing focus on Indigenous peoples of Australia, Asia, and the Pacific. A/Prof Julien Louys and Dr Mark de Bruyn are based in ARCHE and together have a wealth of experience in studying past environmental change, human-faunal interactions through time, and the use of genetic and phylogenetic data to examine evolutionary questions. Dr Tim Maloney is based in GCSCR and an affiliate member of ARCHE and has been working on the archaeology of Australia for nearly 10 years and has a keen interest in the management of feral cat species. Professor Nicole Boivin’s research explores how archaeological data can inform present-day issues ranging from climate change and the Anthropocene to globalization, food security and migration.

Funding Information

The living allowance stipend will be $32,192 per annum tax-free for three years (2023 rate, indexed annually). Project funding to undertake the research, conference travel and incidentals is also provided.

A successful international applicant will also be awarded a Griffith University International Postgraduate Research Scholarship to cover tuition fees for up to three years (noting the onshore requirement mentioned previously). Please see the GUIPRS Conditions of Award for more information.

Special Requirements

The selection of applicants for the award of higher degree research scholarships at Griffith University involves consideration of your academic merit and research background. To be successful research project on aDNA and the impact of feral cats in Australia, you will be able to demonstrate a strong foundation in genetics and molecular biology, as well as familiarity with conservation biology, archaeology/palaeontology, and wildlife management. You will have evidence of a passion for biodiversity conservation and a desire to address the negative impact of feral cats on Australian wildlife. You will ideally have experience in fieldwork, data collection, and analysis, as well as the ability to work independently and collaboratively with stakeholders from diverse backgrounds. with a strong desire to undertake research in making a positive impact on the environment.

Qualifications
Expressions of interest are welcome from domestic and international applicants.
Applicants must have completed, or expect to complete, a bachelors degree with honours equivalent to first class honours or a Masters degree (AQF Level 9) incorporating a significant research component of a standard comparable to a bachelor honours degree or be regarded by Griffith University as having an equivalent level of attainment in accordance with Schedule One of the HDR Scholarship Policy. For further information on the eligibility requirements for the program refer here.
International applicants should ensure that English Language Proficiency requirements for the program are met before formally applying. Applicants to research programs will need to show they meet:

  • A minimum overall band score of 6.5 on the IELTS (Academic) with no band score less than 6.0 OR
  • A minimum score of 575 on the paper-based TOEFL including a score of no less than 5.0 on the TWE OR
  • A score of 79 on the internet-based (iBT) TOEFL with no sub-score less than 19
Additional InformationThis project will be undertaken through the Australian Research Centre for Human Evolution (ARCHE), with cross supervision from the Griffith Centre for Social and Cultural Research (GCSCR) and the Department of Archaeology, Max Planck Institute of Geoanthropology, Germany.
Categories : PhD Health Sciences | PhD Bio, Chemie | GU Projects
Logo RMIT
University:RMIT University
Faculty:Faculty of Science
Project Start Date:flexible
Application Deadline:ongoing
Supervisor Name:Professor Donald Wlodkowic, [email protected]
Location (City/Campus):Bundoora West, Melbourne
Project Description:

Are you an engineer, software developer, or perhaps the AI wizard looking to make a big impact in environmental sciences and drug discovery? We have an exciting PhD project that is perfect for you!

We are seeking talented and innovative PhD candidates to develop algorithms that enable video-based real-time tracking of aquatic model organisms in complex environments on a large scale. This interdisciplinary project will pioneer new algorithms and innovative methods to provide the world's first inherently scalable behavioral bioanalysis, unlocking cognitive research in aquatic eco-neurotoxicology and neuroactive drug discovery. Additionally, the outcomes of the project will enable novel scientific discoveries in neurobiology research on aquatic animals.

The lack of automated and high-throughput cognitive tests in aquatic model organisms is a major deficiency, but with your help, we can change that. This project will provide the first-ever unbiased and automated analytical systems for cognitive eco- & neurotoxicology, allowing us to assess how diverse neuroactive pollutants and/or drugs affect higher neurological functions of aquatic animals.

Don't miss this opportunity to be at the forefront of ground-breaking research at the Neurotox Lab at RMIT University. As one of Australia's leading experts in eco-neurotoxicology, we are exploring how pollutants impact animal behavior and neurodevelopment, as well as elucidating the neurobiological foundations underlying changes in animal behavior.

By joining this PhD project, you will have the opportunity to work in an exciting and rapidly growing interdisciplinary field. Apply now and join us in making a difference in the world.

Funding Information:

The applicants can apply for RMIT Higher Degree by Research International Scholarship upon being granted an offer of admission to an RMIT research training program. The deadline for the next International Scholarship round will be 15th September 2023.

Admission Requirements:Any significant achievements such as e.g. publications will greatly increase the success rate during the scholarship application process.
Categories : PhD Engineering | PhD Bio, Chemie | RMIT
University:University of Adelaide
Faculty:Faculty of Science, Engineering, and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Dr Lukas Gerstweiler; [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:

Preparative chromatography is a key unit operation in biopharmaceutical manufacturing. Flow rate gradients can further improve process economics. This project aims to extend current mechanistic models to precisely model flow rate variations as well as investigate the influence of flow rate gradients on preparative chromatography.

Funding Information:

GOstralia! Research Centre Scholarships

Special Requirements:While you don’t have to be an expert, differential equations shouldn’t scare you. You should also have basic programming skills (matlab, python)
Categories : PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering, and Technology
Project Start Date:01.10.2023
Application Deadline:30.06.2023
Supervisor Name:Dr Danny Wilson, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:Malaria blood stage parasites grow and replicate within human red blood cells (RBCs). The repeated cycles of blood-stage parasite multiplication cause malaria disease and >600,000 deaths/yr. RBC entry requires coordinated secretion of antigens from two clubbed shaped rhoptry organelles positioned near the parasites apical tip. This project will characterise cytosolically exposed rhoptry interacting proteins (C-RIPs) that have essential roles in rhoptry biology. Using advanced gene-editing, proteomics and quantitative super-resolution microscopy techniques, the project will characterise the role of C-RIPs and interacting partners in rhoptry mechanobiology during RBC entry and define key structural regions that could be targeted by drugs.
Funding Information:

GOstralia! Research Centre Scholarships

Special Requirements:Experience in one or more of microbiology, molecular and imaging techniques preferred. Experience in a malaria lab desirable. Demonstrated involvement in data generation and writing of a paper also desirable.
Additional Information:Opportunity to also visit and work in collaborators laboratory in Hamburg for periods of time also possible.
Categories : PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering, and Technology
Project Start Date:01.07.2023
Application Deadline:30.06.2023
Supervisor Name:Stephen P. Kidd, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:This project will directly build on our recent research which has uniquely shown that different bacterial species adopt a range of cell types to enable long term survival during human infection, such as when causing relapsing bone infections. Specifically, a bacterial sub-population of cells with a reduced metabolic rate but tolerance to antimicrobials can also live inside bone cells and thereby act as a reservoir for relapsing infections. This project will describe the molecular pathways that drive the change from a disease-causing cell population to one that is inactive but then reverts to cause a relapsing disease.
Funding Information:

GOstralia! Research Centre Scholarships

Special Requirements:Experience in Microbiology, Molecular Biology, Molecular Evolution
Categories : PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering, and Technology
Project Start Date:01.07.2023
Application Deadline:30.06.2023
Supervisor Name:Phill Cassey, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:This project will determine the drivers of establishment for alien species in Antarctica, through the combination of species attributes and location (or site) -level attributes, and the driving processes of human activity. Biosecurity management requires a flexible and dynamic approach to multi-species risk assessment. The likelihood of establishment will be modelled as biophysical processes from: (i) species-level traits, (including life-cycle, species limits, and resource requirements of the species) ii) location and site attributes (including physical and biotic characteristics and iii) human activity (including reliability of transport and other activities that promote increased numbers (propagules)).
Funding Information:

GOstralia! Research Centre Scholarships

Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University:University of Sydney
Faculty:Faculty of Engineering
Project Start Date:01.03.2023 (later start possible)
Application Deadline:no fix deadline, applications accepted until position is filled
Supervisor Name:A/Prof Arnold Lining Ju - [email protected] 
Location (City/Campus):Sydney / Camperdown
Project Description:

The mechanical stimuli generated by body exercise can be transmitted from cortical bone into the deep bone marrow. A mechanosensitive perivascular stem cell niche is recently identified within the bone marrow for osteogenesis and lymphopoiesis. However, the mechanopropagation from compact bone to deep bone marrow vasculature remains elusive in this fundamental mechanobiology field. No experimental system is available yet to directly understand such exercise‐induced mechanopropagation at the bone‐vessel interface. To this end, an integrated computational biomechanics framework to quantitatively evaluate the mechanopropagation capabilities of bone marrow arterioles, arteries, and sinusoids is devised. The 3D geometries of blood vessels are smoothly reconstructed in the presence of vessel wall thickness and intravascular pulse pressure, followed by finite element analysis to thoroughly investigate the mechanical effects of exercise‐induced intravascular vibratory stretching on bone marrow vasculature. The effects of blood pressure and cortical bone bending are also examined. It is concluded that arterioles and arteries are much more efficient in transducing mechanical force than sinusoids due to their higher stiffness. In the future, this in-silico approach could be combined with other clinical imaging modalities for subject/patient‐specific vascular reconstruction and biomechanical analysis, providing large‐scale phenotypic data for personalized mechanobiology discovery.

Funding Information:

The Scholarship will provide a stipend allowance equivalent to the University of Sydney’s Research Training Program (RTP) stipend rate for up to 3.5 years.

RTP stipend is currently $35,950 AUD/year.

The scholarship is available to domestic and international students.

Admission Requirements:To apply, email academic transcript and resume to supervisor A/Prof Arnold Lining Ju - [email protected]

You will have to have:
• Academic knowledge in the discipline of biophysics, biomechanics, electrophysiology, cell biology and biochemistry;
• Experience of Linux/Unix commanding line (Unix shell)
• Capability of using two or more of ANSYS, COMSOL, Abaqus, LabVIEW, Python, AutoCAD, MATLAB and other software.

Preferred experience include:
• Solid basic knowledge of biology and hands-on experience in PC2 biological laboratory, using flow cytometer, ELISA, Western blots, protein-protein interaction assays, protein/antibody purification and functional characterizations;
• Experience in theoretical simulation using and MATLAB or COMSOL, or LabVIEW programming to control equipment and devices.
• Capability of independently output processing models and drawings, be capable of CNC programming, use other conventional processing platform equipment to manufacture mechanical parts, and use 3D printers for part manufacturing.
• Pre-doctoral track records with publications, conference papers, reports, professional or technical contributions with evidence of independent research ability.
• Excellent oral and written communication skills.
Categories : PhD Health Sciences | PhD Engineering | PhD Bio, Chemie | SYD Projects
University:University of Sydney
Faculty:Faculty of Engineering
Project Start Date:01.03.2023 (later start possible)
Application Deadline:no fix deadline; application open until position is filled
Supervisor Name:A/Prof Arnold Lining Ju - [email protected] 
Location (City/Campus):Sydney / Camperdown
Project Description:

Clotting and bleeding are two sides of a coin, leading to cardiovascular diseases such as stroke and haemophilia—the No.1 worldwide killer. It has long been recognised that the von Willebrand factor (VWF) is the mechanosensor for primary and secondary haemostasis by interacting with platelets and clotting factor VIII. We have recently discovered a new ‘biomechanical’ prothrombotic mechanism that highlights the remarkable VWF sensitivity to the shear stress of blood flow disturbance. Importantly, we found that the current drugs are often not successful and come with an increased financial burden.
To address this pressing need, we are establishing a GPU accelerated multi-scale simulation platform to unveil the effects of blood flow disturbance at the single-molecule level. For the first time, fluid mechanics and biochemistry fields will be united in silico to correlate the haemodynamic parameters with clotting and bleeding disorders.

Funding Information:

The Scholarship will provide a stipend allowance equivalent to the University of Sydney’s Research Training Program (RTP) stipend rate for up to 3.5 years.

RTP stipend is currently $35,950 AUD/year.

The scholarship is available to domestic and international students.

Admission Requirements:To apply, email academic transcript and resume to supervisor A/Prof Arnold Lining Ju - [email protected]

You will have:
• Academic knowledge in the discipline of biophysics, biomechanics, electrophysiology, cell biology and biochemistry;
• Experience of Linux/Unix commanding line (Unix shell)
• Capability of using two or more of GROMACS, Hex, LabVIEW, Python, AutoCAD, MATLAB and other software.

Preferred experience include:
• Solid basic knowledge of biology and hands-on experience in PC2 biological laboratory, using flow cytometer, ELISA, Western blots, protein-protein interaction assays, protein/antibody purification and functional characterizations;
• Experience in theoretical simulation using and MATLAB or COMSOL, or LabVIEW programming to control equipment and devices.
• Capability of independently output processing models and drawings, be capable of CNC programming, use other conventional processing platform equipment to manufacture mechanical parts, and use 3D printers for part manufacturing.
• Pre-doctoral track records with publications, conference papers, reports, professional or technical contributions with evidence of independent research ability.
• Excellent oral and written communication skills.

Categories : PhD Health Sciences | PhD Engineering | PhD Bio, Chemie | SYD Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.09.2023
Application Deadline:30.06.2023
Supervisor Name:Dr Stijn Glorie, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:This project will apply a range of revolutionary in-situ dating methods (Lu-Hf, Re-Os), which were recently developed at the University of Adelaide, to decipher the timing of hydrothermal alteration and mineralisation in the world-class Olympic Province in South Australia. The development of large iron-oxide copper-gold deposits in this area was a staged process, with an initial event in the early Mesoproterozoic and at least one `upgrading` event in the late Neoproterozoic-Cambrian. The latter event induced fluid flow that might have transported metals from the fertile IOCG basement towards strataboud deposits. The project will assess this temportal link, which will have great implications for future mineral exploration endeavours.
Funding Information:

GOstralia! Research Centre Scholarships

Additional Information:

More info on the novel dating methods can be found in:

www.sciencedirect.com/science/article/pii/S0009254121002436

onlinelibrary.wiley.com/doi/full/10.1111/ter.12580

gchron.copernicus.org/articles/4/353/2022/

www.lyellcollection.org/doi/10.1144/SP537-2022-205

Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Shervin Kabiri, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:Australia is faced with a big contamination problem relating to chemicals used in firefighting foams, called per- and poly-fluoroalkyl substances or PFAS. PFAS are a large group of chemicals, with over 5000 different species. Their complexity has posed a challenge with existing remediation approaches based on sorbents, with varying success achieved for different PFAS species. For example, current sorbents available in the market cannot effectively immobilise short-chain PFAS.This project aims to develop remediation materials that will be effective for a wider range of PFAS and allow tailored solutions for PFAS immobilisation in soil. This project will assist the PhD student to develop skills in material and soil science, environmental chemistry, analytical techniques and soil management. It also provides an opportunity for the student to work with the industry.
Funding Information:

GOstralia! Research Centre Scholarships

Special Requirements:The applicant should have good track record of publication.
Additional Information:The successful student will be located at the University of Adelaide’s Waite Campus, working at CSIROs research facility as well as the School of Agriculture. The in-business component of the degree will be conducted at Rembind’s Head Office (2 Ann Nelson Drive, Thebarton SA 5031), but will also involve some interstate travel to remediation projects and manufacturing facilities.
Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Cassandra Collins, [email protected]; co-supervisor: Shashi Goonetilleke, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:Sweet kernel in almond has been found to be a heterozygous trait and the bitter kernel to be recessive. Usually, about 25% of the progeny in the Australian almond breeding program have bitter kernels. Presently, plants with bitter almonds will be discarded once they are found to be bitter after 3-4 years in the orchards. Therefore, sweet almonds remain a major breeding target in almond breeding. The gene encodes the sweetness in almond belongs to linkage group five, however, the precise location is still unknown. The broad objective of this project is to identify the genomic regions that affect bitter kernels and evaluate the potential of CRISPR/Cas9 mediated technologies to eliminate the bitterness in almond kernels.
Funding Information:

GOstralia! Research Centre Scholarships

Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Dr Stephanie Watts-Fawkes, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:This project will investigate the effects of beneficial mycorrhizal fungi on crop nutrition. The mycorrhizal pathway of phosphorus uptake is important for plants, but may lead to increased accumulation of the anti-nutrient compound phytate in grains and pulses. This project will uncover how mycorrhizal fungi affect phytate accumulation in the edible portion of crops, and how this modifies the bioavailability of micronutrients such as zinc and iron for human consumption. The PhD candidate will inoculate plants with mycorrhizal fungi and grow them until maturity. The resulting grain samples will be analysed for bioavailability and bioaccessibility of Zn and Fe.
Funding Information:

GOstralia! Research Centre Scholarships

Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Matthew Gilliham, [email protected] and Jenny Mortimer, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:This project will re-wire plants to optimise their growth in controlled conditions on Earth and in Space. By 2028, humans will have returned to the moon as a precursor to crewed Mars missions but key challenges for mission planners still exist, including: Nutritious, varied foods to sustain physical and mental well-being for humans during long-term Space habitation; and, technology to provide on-demand generation of resources such as pharmaceuticals and construction materials. Space habitation amplifies the multi-faceted sustainability challenges we face in food and biomaterial production on Earth, and can be used to improve sustainable food production on Earth.
Funding Information:

GOstralia! Research Centre Scholarships

Additional Information:Please see here: www.plants4space.com; this project can be conducted in collaboration with the German Space Agency, and or other international partners, please see web-address above for more details.
Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Matthew Denton, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:We are looking to recruit a PhD student to work on this exciting, well-funded, project. The successful applicant will have scope to develop a project that focuses on plant physiology or molecular ecology and/or plant phenomics, in collaboration with supervisors.
Funding Information:

GOstralia! Research Centre Scholarships

Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
University of Melbourne logo
University:University of Melbourne
Faculty:Medicine, Dentistry and Health Sciences
Project Start Date:negotiable
Application Deadline:ongoing
Supervisor Name:Dr Rachael Moses, e-mail: [email protected]
Location (City/Campus):Parkville Precinct
 
Project Description:Humans heal in a different manner to rodents, so we need to start using more representative wound healing models to replicate the tissue architecture and wound healing cascade observed in human dermal wound healing. This exciting PhD opportunity involves developing a 3D infected chronic wound model, comprised of culturing dermal chronic wound fibroblasts, which are obtained from venous leg ulcers and epidermal keratinocytes in a complex 3D model system, allowing the strong paracrine feedback system to occur between the two cell types, as occurs in the native skin environment. This model will be utilising mostly animal-free-origin products, in a move away from typically animal-derived components used in tissue culture, resulting in reduced ethical implications and reduced variability across experiments, due to batch-to-batch variability associated with animal-derived products. This model will use a synthetic hydrogel (PeptiGel®) from Manchester BIOGEL to replace the typically used Matrigel; this PeptiGel® can be tailored to include additional components, including collagen, laminin and fibronectin.

This project involves working within the Sloan/Moses lab at The University of Melbourne, benefitting from their extensive 3D model experience. Dr Moses has been awarded a number of grants and prizes recently to further develop this work, with a strong background in wound healing, in vitro 3D models and novel pharmaceutical screening. Professor Sloan has long standing expertise in developing novel in vitro / ex vivo organ 3D culture model systems for tissue regeneration/engineering and testing novel therapeutic agents, along with advancing the 3Rs in biomedical research and bioengineering. Dr Farrugia has a strong background in biomaterial development and characterisation, and wound healing, including in vitro models, with an additional focus on the development of new therapies. Dr Liam Sharkey is a bacteriologist specialising in antibiotic resistance with a particular focus on Staphylococcus aureus, a common cause of chronic wound infections. He has experience with in vitro models of S. aureus biofilm formation and the genetic manipulation of clinical S. aureus strains. This project benefits from collaboration with industrial partners assessing novel pharmaceuticals on these models; these natural pharmaceuticals have previously been assessed by Dr Moses through a variety of other 2D wound healing studies.

This project will involve a variety of laboratory-based techniques including tissue culture, 3D models, bacteriology, histology, immunostaining, H&E staining, confocal imaging, translational research, bioinformatics, biostatistics, research management, oral presentation skills, and scientific writing skills.
Funding Information:RTP scholarships are available to domestic and overseas students enrolled in an accredited HDR course at an Australian HEP. More information
Categories : PhD Health Sciences | PhD Engineering | PhD Bio, Chemie | MELB Projects
University:University of Adelaide
Faculty:Faculty of Science, Engineering and Technology
Project Start Date:01.08.2023
Application Deadline:30.06.2023
Supervisor Name:Jamie Wood, [email protected]
Location (City/Campus):North Terrace, Adelaide
 
Project Description:Pathogens are a large and crucial component of global biodiversity. However, changes in pathogen communities and populations caused by climate change have the potential to impact host health and disrupt global ecosystems. Our understanding of how climate change affects pathogens is poor, and lacks a long-term perspective. This project will look to use ancient DNA from animal dung and sediment cores to reconstruct how animal and plant pathogens responded to actual climate change events in the past. These unique ‘real-time’ insights into long-term processes will help answer pivotal questions in pathogen ecology and help inform modelling of emerging pathogen risks.
Funding Information:

GOstralia! Research Centre Scholarships

Categories : PhD Earth Sciences | PhD Bio, Chemie | ADL Projects
Logo RMIT
University:RMIT University
Faculty:Faculty of Science
Project Start Date:flexible
Application Deadline:ongoing
Supervisor Name:Professor Donald Wlodkowic, [email protected]
Location (City/Campus):Bundoora West, Melbourne
Project Description:

Looking to make a real difference in the world of environmental science? Join the Neurotox Lab at RMIT University and help us tackle the urgent issue of aquatic pollution. With an ever-increasing number of contaminants entering our waterways, we need your help to understand the ecological and behavioral consequences of exposure to these substances.

As a PhD candidate in our lab, you'll have the opportunity to focus on aquatic animals that interest you, from planarians and crustaceans to insects, snails, and fish. With access to cutting-edge techniques in behavioral ecotoxicology, you'll be able to investigate how exposure to emerging toxicants like pharmaceuticals, PFAS, and micro-/nanoplastics can impact animal behavior at the most fundamental, functional level.

Using state-of-the-art video tracking and advanced biotests, you'll develop new insights into the functional effects of contaminants on animal behavior. From unstimulated behaviors to phototaxis, thermal preference and cognitive responses, you'll explore a wide range of behavioral phenotypes, and help us identify the unique neurobiological mechanisms that underlie these changes.

At the Neurotox Lab, you'll be part of a world-class team who are making a real difference in the emerging field of eco-neurotoxicology. With a focus on understanding the complex relationships between pollution, animal behavior, and ecological consequences, we're helping to shape the future of environmental science.

So if you're looking for a PhD project that can truly make a difference, join us today on a great science adventure in Australia and become part of the solution to environmental challenges.

Funding Information:

The applicants can apply for RMIT Higher Degree by Research International Scholarship upon being granted an offer of admission to an RMIT research training program. The deadline for the next International Scholarship round will be 15th September 2023.

Admission Requirements:Any significant achievements such as e.g. publications will greatly increase the success rate during the scholarship application process.
Categories : PhD Earth Sciences | PhD Bio, Chemie | RMIT
Logo RMIT
University:RMIT University
Faculty:Faculty of Science
Project Start Date:flexible
Application Deadline:ongoing
Supervisor Name:Professor Donald Wlodkowic, [email protected]
Location (City/Campus):Bundoora West, Melbourne
Project Description:

Attention all PhD candidates with a passion for aquatic animals and the environment! We have an exciting opportunity for you to pioneer a ground-breaking project that will unlock the secrets of thermal preference behaviors in aquatic animals.

This multi-species screening project will uncover the intertwined aspects of temperature sensing and neuronal data processing that are fundamental for dynamic thermal adaptations and ecological fitness.

You will be part of an interdisciplinary team at the Neurotox Lab at RMIT University, one of Australia's leading experts in eco-neurotoxicology. Using state-of-the-art techniques including quantitative computer animal tracking, you will undertake a pioneering multi-species screening of thermotactic responses in aquatic animals, from native Australian invertebrates to fish. This part of the project will lay the foundation for the development of innovative ecotoxicity biotests.

But the project doesn't stop there! In the following stages, you will explore and make new discoveries on how exposure to emerging contaminants, such as pharmaceuticals, PFAS, and micro/nanoplastics, can alter thermal preference behaviors. This is of considerable importance, as thermal preference behaviors in aquatic animals can become key behavioral factors in toxicological assessment.

Join us at the forefront of this exciting and rapidly growing interdisciplinary field, and be part of a team that is making a difference in the world. Apply now to the Neurotox Lab at RMIT University and discover the world of thermal preference behaviors in aquatic animals.

Funding Information:

The applicants can apply for RMIT Higher Degree by Research International Scholarship upon being granted an offer of admission to an RMIT research training program. The deadline for the next International Scholarship round will be 15th September 2023.

Admission Requirements:Any significant achievements such as e.g. publications will greatly increase the success rate during the scholarship application process.
Categories : PhD Earth Sciences | PhD Bio, Chemie | RMIT

Grundlegendes zum Schwerpunkt Bio- und Chemiewissenschaften

Im Mittelpunkt der Biologiewissenschaften stehen alle grundlegenden Aspekte lebender Organismen: Mikroorganismen, Pilze, Pflanzen und Tiere. Viele Forschungsgruppen arbeiten mit interdisziplinären Fragestellungen und untersuchen, wie Arten und Ökosysteme verwaltet, erhalten und wiederhergestellt werden können. Mit modernen Techniken und Methoden, die von molekularen und genetischen Analysen bis hin zu Big-Data-Sciences reichen, werden komplexe Zusammenhänge erforscht.  

Wie die Biologie so spielt auch die Chemie in allen Bereichen unseres Lebens eine grundlegende Rolle. Zentrale Bedeutung hat die Entwicklung neuer Medikamente für die Behandlung von Krankheiten und die Entwicklung innovativer Materialien.Australische Hochschulen zeichnen sich durch hervorragende Grundlagen- und angewandte Forschung aus, deren Ergebnisse eine bedeutende Rolle für die chemische Industrie weltweit darstellen. 

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